06.03.2018., 9:15 am., room 1.03.
“The construction of a DNA aptamer library based on new modified nucleotides and its use for the selection of aptamers towards the N-terminal domain of human MDM2 protein”.
Przemysław Jurek, Pure Biologics S.A.
Supervisor: dr hab. Małgorzata Zakrzewska, Department of Protein Engineering.

Presentation will be in Polish.

The figure depicts a simplified scheme for obtaining modified aptamers using the SELEX technique, and a structure of one of the new modified nucleotides based on a thymidine residue with a chlorobenzyl group coupled to the pyrimidine ring via a „click chemistry” reaction.