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Department of Molecular Microbiology

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Department Website

Head

Staff

PhD Students

(phone: 71-375-2393, -2640, rooms: 3.17, 3.18)


In the Department of Molecular Microbiology we study the basic bacterial

cell biology processes:

  • chromosome replication and the regulation of this process,
  • the influence of chromosome topology on replication,
  • regulation of genes expression, including those involved in secondary metabolites (antibiotics) production,
  • chromosome segregation and its coordination with cell division and other cell cycle processes,
  • chromosome organisation during bacterial cell cycle

 Research Projects:

  • 2019 – 2022: Research project NCN OPUS 15, (2018/29/B/NZ6/00539) “Bdellovibrio bacteriovorus, a ‘living antibiotic’ – life cycle dynamics during predation on different pathogens” Principal investigator – J. Zakrzewska-Czerwińska

  • 2018 – 2021: Research project NCN OPUS 14, (2017/27/B/NZ1/00823) “Mechanism of mycobacterial chromosome segregation – the role of proteins interacting with ParA” Principal investigator -D. Jakimowicz

  • 2018 – 2021: Research project NCN SONATINA 2, (2018/28/C/NZ1/00241) Role of the interaction between HupA and HupS proteins during Streptomyces growth and stress response.” Principal Investigator – Agnieszka Strzałka

  • 2017 – 2020: Research project NCN OPUS 13, (2017/25/B/NZ1/00657) „Mycobacterial Lsr2 protein as a global chromosomal organizer and transcription factor – an interplay of Lsr2 with SMC complex and HupB”
    Principal investigator – J. Zakrzewska-Czerwinska

  • 2017 – 2020: Research project NCN SONATINA 2, (2018/28/C/NZ1/00128) „Rola białka mIHF w organizacji chromosomu Mycobacterium oraz jego wpływ na ekspresję genów”
    Principal investigator – J. Hołówka

  • 2017 – 2020: Research project NCN HARMONIA 8 programme, “The architecture of bacterial segrosome – the cooperation of topoisomerase I and segregation protein ParB in Streptomyces.” Principal investigator – M. Szafran

  • 2015 – 2019: Research project NCN OPUS 8 programme 2015 – 2018 “Chromosome topology as a global regulator of gene transcription – interplay between topoisomerases and nucleoid binding proteins in bacteria adaptation to stress conditions” Principal investigator – D. Jakimowicz

Publications