28.05.2019., 9:15 am., room 1.03.
“Searching for novel proteins cooperating with topoisomerase I in bacteria Streptomyces coelicolor“.
Mgr Martyna Gongerowska.

Supervisor:  prof. dr hab. Dagmara Jakimowicz
Department of Molecular Microbiology.

Presentation will be in Polish.

In topoisomerase I (TopA) depletion background the nucleoid is highly condensed, what inhibits sporulation. Novel two component system SCO3389-3390 is capable to activate transcription of supercoiling hypersensitive cluster (SHC) what blocks sporulation.